by Inge Jager, Pelle de Koning, Tim Bost, Damiaan Denys, Nienke Vulink
Objective Analyze a large sample with detailed clinical data of misophonia subjects in order to determine the psychiatric, somatic and psychological nature of the condition.
Methods This observational study of 779 subjects with suspected misophonia was conducted from January 2013 to May 2017 at the outpatient-clinic of the Amsterdam University Medical Centers, location AMC, the Netherlands. We examined DSM-IV diagnoses, ...
Source: PLOSOne
Published: Wed, 15 Apr 2020 23:00 UTC
by Lorenz Ertl, Hartmut Brückmann, Maximilian Patzig, Franziska Dorn, Gunther Fesl
Purpose Patient-reported long-term follow-up after endovascular treatment of indirect carotid cavernous fistulas is important, but rarely addressed in literature. We report on this issue with a special focus on the patient’s view and its impact on the indication evaluation process.
Methods We retrospectively reviewed the records of all patients (n = 33) with a minimum follow-up interval of at least 36 and up to ...
Source: PLOSOne
Published: Fri, 10 Apr 2020 23:00 UTC
by Jeon Mi Lee, Hyun Jin Lee, In Seok Moon, Jae Young Choi
Objectives Tinnitus is a common symptom among patients with hearing loss, and many studies have reported successful tinnitus suppression with hearing devices. Active middle ear implantation of the Vibrant Soundbridge (VSB) is a good alternative to existing hearing devices. This study evaluated the effects of VSB implantation on tinnitus and sought to identify the main audiological factor that affects tinnitus suppression.
Methods The ...
Source: PLOSOne
Published: Tue, 04 Feb 2020 23:00 UTC
by Uli Niemann, Benjamin Boecking, Petra Brueggemann, Wilhelm Mebus, Birgit Mazurek, Myra Spiliopoulou
Background Chronic tinnitus is a complex condition that can be associated with considerable distress. Whilst cognitive-behavioral treatment (CBT) approaches have been shown to be effective, not all patients benefit from psychological or psychologically anchored multimodal therapies. Determinants of tinnitus-related distress thus provide valuable information about tinnitus characterization and ...
Source: PLOSOne
Published: Thu, 30 Jan 2020 23:00 UTC
by Yi-Chun Chen, Shiang-Jiun Tsai, Jin-Cherng Chen, Juen-Haur Hwang
Tinnitus and hearing impairment are prevalent among headache patients. This study aims to investigate the risk of tinnitus, sensorineural hearing impairment, and sudden deafness in patients with non-migraine headache. Participants included 43 294 patients with non-migraine headache (non-migraine headache cohort) and 173 176 patients with no headache of any type (control cohort) frequency-matched with respect to 10-year age ...
Source: PLOSOne
Published: Fri, 06 Sep 2019 23:00 UTC
by Weihua Wang, Li. S. Zhang, Alexander K. Zinsmaier, Genevieve Patterson, Emily Jean Leptich, Savannah L. Shoemaker, Tatiana A. Yatskievych, Robert Gibboni, Edward Pace, Hao Luo, Jinsheng Zhang, Sungchil Yang, Shaowen Bao
Hearing loss is a major risk factor for tinnitus, hyperacusis, and central auditory processing disorder. Although recent studies indicate that hearing loss causes neuroinflammation in the auditory pathway, the mechanisms underlying hearing loss–related pathologies are still ...
Source: PLOSOne
Published: Tue, 18 Jun 2019 23:00 UTC
by Eric Samarut, Domitille Chalopin, Raphaëlle Riché, Marc Allard, Meijiang Liao, Pierre Drapeau
Glycine receptors (GlyRs) are ligand-gated chloride channels mediating inhibitory neurotransmission in the brain stem and spinal cord. They function as pentamers composed of alpha and beta subunits for which 5 genes have been identified in human (GLRA1, GLRA2, GLRA3, GLRA4, GLRB). Several in vitro studies showed that the pentameric subtype composition as well as its stoichiometry influence the ...
Source: PLOSOne
Published: Thu, 02 May 2019 23:00 UTC
by Natalia Yakunina, Sam Soo Kim, Eui-Cheol Nam
Objective Vagus nerve stimulation (VNS) is a neuromodulation method used for treatment of epilepsy and depression. Transcutaneous VNS (tVNS) has been gaining popularity as a noninvasive alternative to VNS. Previous tVNS neuroimaging studies revealed brain (de)activation patterns that involved multiple areas implicated in tinnitus generation and perception. In this study, functional magnetic resonance imaging (fMRI) was used to explore the effects of ...
Source: PLOSOne
Published: Wed, 28 Nov 2018 23:00 UTC
by Do-Yang Park, Hyun Jun Kim, Chang-Hoon Kim, Jae Yong Lee, Kyungdo Han, Ji Ho Choi
Olfactory dysfunction and tinnitus are age-related otorhinolaryngological disorders with a high prevalence in the elderly population and share several common clinical features. However, there is no study investigating the relationship between these two diseases. We studied the prevalence of olfactory dysfunction and tinnitus among Koreans and studied the relationship between these two diseases based on the Korean ...
Source: PLOSOne
Published: Tue, 23 Oct 2018 23:00 UTC
by Daniël O. J. Reijntjes, Nick M. A. Schubert, Alexander Pietrus-Rajman, Pim van Dijk, Sonja J. Pyott
Approaches to identify the perception of tinnitus in various animal models have been difficult to apply to mouse. As a result, mice have been underutilized to investigate the cellular, molecular, and genetic mechanisms underlying tinnitus. A recent study in guinea pigs identified a novel spontaneous behavior (unconditioned response), changes in movement during silent gaps, that identified a ...
Source: PLOSOne
Published: Wed, 29 Aug 2018 23:00 UTC
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