Tinnitus Centralthe latest tinnitus news from all over the net

News from PLOSOne

Electrophysiological assessment and pharmacological treatment of blast-induced tinnitus

by Jianzhong Lu, Matthew B. West, Xiaoping Du, Qunfeng Cai, Donald L. Ewert, Weihua Cheng, Don Nakmali, Wei Li, Xiangping Huang, Richard D. Kopke
Tinnitus, the phantom perception of sound, often occurs as a clinical sequela of auditory traumas. In an effort to develop an objective test and therapeutic approach for tinnitus, the present study was performed in blast-exposed rats and focused on measurements of auditory brainstem responses (ABRs), prepulse inhibition of the acoustic startle response, ...

Source: PLOSOne
Published: Thu, 07 Jan 2021 15:00 UTC

Factors affecting the implementation of evidence-based Progressive Tinnitus Management in Department of Veterans Affairs Medical Centers

by Tara L. Zaugg, Emily J. Thielman, Kathleen F. Carlson, Anaïs Tuepker, Christine Elnitsky, Karen L. Drummond, Caroline J. Schmidt, Summer Newell, Christine Kaelin, Christie Choma, James A. Henry
Purpose Progressive Tinnitus Management (PTM) is an evidence-based interdisciplinary stepped-care approach to improving quality of life for patients with tinnitus. PTM was endorsed by Department of Veterans Affairs (VA) Audiology leadership in 2009. Factors affecting implementation of PTM are unknown. We ...

Source: PLOSOne
Published: Mon, 28 Dec 2020 15:00 UTC

Systematic review and meta-analysis of late auditory evoked potentials as a candidate biomarker in the assessment of tinnitus

by Emilie Cardon, Iris Joossen, Hanne Vermeersch, Laure Jacquemin, Griet Mertens, Olivier M. Vanderveken, Vedat Topsakal, Paul Van de Heyning, Vincent Van Rompaey, Annick Gilles
Subjective tinnitus, the perception of sound in the absence of any sound source, is routinely assessed using questionnaires. The subjective nature of these tools hampers objective evaluation of tinnitus presence, severity and treatment effects. Late auditory evoked potentials (LAEPs) might be considered as a potential ...

Source: PLOSOne
Published: Thu, 17 Dec 2020 15:00 UTC

Objective measurement of tinnitus using functional near-infrared spectroscopy and machine learning

by Mehrnaz Shoushtarian, Roohallah Alizadehsani, Abbas Khosravi, Nicola Acevedo, Colette M. McKay, Saeid Nahavandi, James B. Fallon
Chronic tinnitus is a debilitating condition which affects 10–20% of adults and can severely impact their quality of life. Currently there is no objective measure of tinnitus that can be used clinically. Clinical assessment of the condition uses subjective feedback from individuals which is not always reliable. We investigated the sensitivity of functional ...

Source: PLOSOne
Published: Wed, 18 Nov 2020 15:00 UTC

Effect of age on the gap-prepulse inhibition of the cortical N1-P2 complex in humans as a step towards an objective measure of tinnitus

by Yunseo Ku, Do Youn Kim, Chiheon Kwon, Tae Soo Noh, Moo Kyun Park, Jun Ho Lee, Seung Ha Oh, Hee Chan Kim, Myung-Whan Suh
The gap-prepulse inhibition of the acoustic startle reflex has been widely used as a behavioral method for tinnitus screening in animal studies. The cortical-evoked potential gap-induced inhibition has also been investigated in animals as well as in human subjects. The present study aimed to investigate the effect of age on the cortical N1-P2 complex in the gap-prepulse ...

Source: PLOSOne
Published: Thu, 05 Nov 2020 15:00 UTC

Pharmacologic and surgical therapies for patients with Meniere’s disease: A systematic review and network meta-analysis

by Nadera Ahmadzai, Wei Cheng, Shaun Kilty, Leila Esmaeilisaraji, Dianna Wolfe, James Bonaparte, David Schramm, Elizabeth Fitzpatrick, Vincent Lin, Becky Skidmore, Brian Hutton
Background Meniere’s disease (MD) is a chronic condition of the inner ear consisting of symptoms that include vertigo attacks, fluctuating sensorineural hearing loss, tinnitus and aural fullness. Despite availability of various interventions, there is uncertainty surrounding their relative efficacy, thus making it difficult ...

Source: PLOSOne
Published: Tue, 01 Sep 2020 16:00 UTC

Improved measurement of tinnitus severity: Study of the dimensionality and reliability of the Tinnitus Handicap Inventory

by Elzbieta Gos, Adam Sagan, Piotr H. Skarzynski, Henryk Skarzynski
Objective The Tinnitus Handicap Inventory (THI) is widely used in clinical practice and research as a three-dimensional measure of tinnitus severity. Despite extensive use, its factor structure remains unclear. Furthermore, THI can be considered a reliable measure only if Cronbach’s alpha coefficient and Classical Test Theory is used. The more modern and robust Item Response Theory (IRT) has so far not been used to psychometrically ...

Source: PLOSOne
Published: Tue, 25 Aug 2020 16:00 UTC

Electrophysiological correlates of focused attention on low- and high-distressed tinnitus

by Rafal Milner, Monika Lewandowska, Malgorzata Ganc, Jan Nikadon, Iwona Niedzialek, Wieslaw Wiktor Jedrzejczak, Henryk Skarzynski
Objectives The study aimed at determining the EEG correlates of concentration on either low or high-distressed tinnitus.
Methods Sixty-seven patients (36 women, mean age = 50.34 ± 12.94 years) with chronic tinnitus were assigned to either a high (HD) or low (LD) tinnitus-related distress group based on THI results. All participants took part in the EEG study ...

Source: PLOSOne
Published: Wed, 05 Aug 2020 16:00 UTC

Prevalence, associated factors, and comorbidities of tinnitus in adolescents

by Jihye Rhee, Dongwook Lee, Myung Whan Suh, Jun Ho Lee, Yun-Chul Hong, Seung Ha Oh, Moo Kyun Park
The aim of this study was to investigate the prevalence of tinnitus among adolescents, and the factors known or hypothesized to be associated with tinnitus. Based on random sampling of school types and regions, a nationwide hearing survey of the first-year middle and high school students of South Korea was performed. The subjects underwent an otologic examination followed by pure tone audiometry up ...

Source: PLOSOne
Published: Fri, 31 Jul 2020 16:00 UTC

Idiopathic intracranial hypertension in patients with anemia: A retrospective observational study

by Zhonghua Ma, Hanqiu Jiang, Chao Meng, Shilei Cui, Jingting Peng, Jiawei Wang
Idiopathic intracranial hypertension (IIH) mostly affects obese women in childbearing age, leading to frustrating headache and permanent visual impairment. The exact etiology of this condition is poorly understood, and the population at risk and clinical presentation seems to be homogeneous. However, little attention has been paid to the clinical features of IIH patients with anemia. We herein performed a retrospective ...

Source: PLOSOne
Published: Fri, 31 Jul 2020 16:00 UTC